Search | VHL Search Portal

1.

Gene expression networks regulated by human personality.

Del Val, Coral; Díaz de la Guardia-Bolívar, Elisa; Zwir, Igor; Mishra, Pashupati P; Mesa, Alberto; Salas, Ramiro; Poblete, Guillermo F; de Erausquin, Gabriel; Raitoharju, Emma; Kähönen, Mika; Raitakari, Olli; Keltikangas-Järvinen, Liisa; Lehtimäki, Terho; Cloninger, Claude Robert.

Mol Psychiatry ; 2024 Mar 04.

Article in English | MEDLINE | ID: mdl-38433276

2.

Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait loci.

Laaksonen, Jaakko; Mishra, Pashupati P; Seppälä, Ilkka; Raitoharju, Emma; Marttila, Saara; Mononen, Nina; Lyytikäinen, Leo-Pekka; Kleber, Marcus E; Delgado, Graciela E; Lepistö, Maija; Almusa, Henrikki; Ellonen, Pekka; Lorkowski, Stefan; März, Winfried; Hutri-Kähönen, Nina; Raitakari, Olli; Kähönen, Mika; Salonen, Jukka T; Lehtimäki, Terho.

Hum Mol Genet ; 31(10): 1720-1732, 2022 05 19.

Article in English | MEDLINE | ID: mdl-35077545

3.

Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.

Nath, Artika P; Ritchie, Scott C; Grinberg, Nastasiya F; Tang, Howard Ho-Fung; Huang, Qin Qin; Teo, Shu Mei; Ahola-Olli, Ari V; Würtz, Peter; Havulinna, Aki S; Santalahti, Kristiina; Pitkänen, Niina; Lehtimäki, Terho; Kähönen, Mika; Lyytikäinen, Leo-Pekka; Raitoharju, Emma; Seppälä, Ilkka; Sarin, Antti-Pekka; Ripatti, Samuli; Palotie, Aarno; Perola, Markus; Viikari, Jorma S; Jalkanen, Sirpa; Maksimow, Mikael; Salmi, Marko; Wallace, Chris; Raitakari, Olli T; Salomaa, Veikko; Abraham, Gad; Kettunen, Johannes; Inouye, Michael.

Am J Hum Genet ; 105(6): 1076-1090, 2019 12 05.

Article in English | MEDLINE | ID: mdl-31679650

4.

Three genetic-environmental networks for human personality.

Zwir, Igor; Del-Val, Coral; Arnedo, Javier; Pulkki-Råback, Laura; Konte, Bettina; Yang, Sarah S; Romero-Zaliz, Rocio; Hintsanen, Mirka; Cloninger, Kevin M; Garcia, Danilo; Svrakic, Dragan M; Lester, Nigel; Rozsa, Sandor; Mesa, Alberto; Lyytikäinen, Leo-Pekka; Giegling, Ina; Kähönen, Mika; Martinez, Maribel; Seppälä, Ilkka; Raitoharju, Emma; de Erausquin, Gabriel A; Mamah, Daniel; Raitakari, Olli; Rujescu, Dan; Postolache, Teodor T; Gu, C Charles; Sung, Joohon; Lehtimäki, Terho; Keltikangas-Järvinen, Liisa; Cloninger, C Robert.

Mol Psychiatry ; 26(8): 3858-3875, 2021 08.

Article in English | MEDLINE | ID: mdl-31748689

5.

Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study.

Laaksonen, Jaakko; Seppälä, Ilkka; Raitoharju, Emma; Mononen, Nina; Lyytikäinen, Leo-Pekka; Waldenberger, Melanie; Illig, Thomas; Lepistö, Maija; Almusa, Henrikki; Ellonen, Pekka; Hutri-Kähönen, Nina; Juonala, Markus; Kähönen, Mika; Raitakari, Olli; Salonen, Jukka T; Lehtimäki, Terho.

Hum Mol Genet ; 28(8): 1381-1391, 2019 04 15.

Article in English | MEDLINE | ID: mdl-30629177

6.

Uncovering the complex genetics of human temperament.

Zwir, Igor; Arnedo, Javier; Del-Val, Coral; Pulkki-Råback, Laura; Konte, Bettina; Yang, Sarah S; Romero-Zaliz, Rocio; Hintsanen, Mirka; Cloninger, Kevin M; Garcia, Danilo; Svrakic, Dragan M; Rozsa, Sandor; Martinez, Maribel; Lyytikäinen, Leo-Pekka; Giegling, Ina; Kähönen, Mika; Hernandez-Cuervo, Helena; Seppälä, Ilkka; Raitoharju, Emma; de Erausquin, Gabriel A; Raitakari, Olli; Rujescu, Dan; Postolache, Teodor T; Sung, Joohon; Keltikangas-Järvinen, Liisa; Lehtimäki, Terho; Cloninger, C Robert.

Mol Psychiatry ; 25(10): 2275-2294, 2020 10.

Article in English | MEDLINE | ID: mdl-30279457

7.

Uncovering the complex genetics of human character.

Zwir, Igor; Arnedo, Javier; Del-Val, Coral; Pulkki-Råback, Laura; Konte, Bettina; Yang, Sarah S; Romero-Zaliz, Rocio; Hintsanen, Mirka; Cloninger, Kevin M; Garcia, Danilo; Svrakic, Dragan M; Rozsa, Sandor; Martinez, Maribel; Lyytikäinen, Leo-Pekka; Giegling, Ina; Kähönen, Mika; Hernandez-Cuervo, Helena; Seppälä, Ilkka; Raitoharju, Emma; de Erausquin, Gabriel A; Raitakari, Olli; Rujescu, Dan; Postolache, Teodor T; Sung, Joohon; Keltikangas-Järvinen, Liisa; Lehtimäki, Terho; Cloninger, C Robert.

Mol Psychiatry ; 25(10): 2295-2312, 2020 10.

Article in English | MEDLINE | ID: mdl-30283034

8.

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.

Ahola-Olli, Ari V; Würtz, Peter; Havulinna, Aki S; Aalto, Kristiina; Pitkänen, Niina; Lehtimäki, Terho; Kähönen, Mika; Lyytikäinen, Leo-Pekka; Raitoharju, Emma; Seppälä, Ilkka; Sarin, Antti-Pekka; Ripatti, Samuli; Palotie, Aarne; Perola, Markus; Viikari, Jorma S; Jalkanen, Sirpa; Maksimow, Mikael; Salomaa, Veikko; Salmi, Marko; Kettunen, Johannes; Raitakari, Olli T.

Am J Hum Genet ; 100(1): 40-50, 2017 Jan 05.

Article in English | MEDLINE | ID: mdl-27989323

9.

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.

Eicher, John D; Chami, Nathalie; Kacprowski, Tim; Nomura, Akihiro; Chen, Ming-Huei; Yanek, Lisa R; Tajuddin, Salman M; Schick, Ursula M; Slater, Andrew J; Pankratz, Nathan; Polfus, Linda; Schurmann, Claudia; Giri, Ayush; Brody, Jennifer A; Lange, Leslie A; Manichaikul, Ani; Hill, W David; Pazoki, Raha; Elliot, Paul; Evangelou, Evangelos; Tzoulaki, Ioanna; Gao, He; Vergnaud, Anne-Claire; Mathias, Rasika A; Becker, Diane M; Becker, Lewis C; Burt, Amber; Crosslin, David R; Lyytikäinen, Leo-Pekka; Nikus, Kjell; Hernesniemi, Jussi; Kähönen, Mika; Raitoharju, Emma; Mononen, Nina; Raitakari, Olli T; Lehtimäki, Terho; Cushman, Mary; Zakai, Neil A; Nickerson, Deborah A; Raffield, Laura M; Quarells, Rakale; Willer, Cristen J; Peloso, Gina M; Abecasis, Goncalo R; Liu, Dajiang J; Deloukas, Panos; Samani, Nilesh J; Schunkert, Heribert; Erdmann, Jeanette; Fornage, Myriam.

Am J Hum Genet ; 99(1): 40-55, 2016 Jul 07.

Article in English | MEDLINE | ID: mdl-27346686

10.

Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation.

Rinne, Petteri; Guillamat-Prats, Raquel; Rami, Martina; Bindila, Laura; Ring, Larisa; Lyytikäinen, Leo-Pekka; Raitoharju, Emma; Oksala, Niku; Lehtimäki, Terho; Weber, Christian; van der Vorst, Emiel P C; Steffens, Sabine.

Arterioscler Thromb Vasc Biol ; 38(11): 2562-2575, 2018 11.

Article in English | MEDLINE | ID: mdl-30354245

11.

Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages.

Rinne, Petteri; Rami, Martina; Nuutinen, Salla; Santovito, Donato; van der Vorst, Emiel P C; Guillamat-Prats, Raquel; Lyytikäinen, Leo-Pekka; Raitoharju, Emma; Oksala, Niku; Ring, Larisa; Cai, Minying; Hruby, Victor J; Lehtimäki, Terho; Weber, Christian; Steffens, Sabine.

Circulation ; 136(1): 83-97, 2017 Jul 04.

Article in English | MEDLINE | ID: mdl-28450348

12.

Blood pathway analyses reveal differences between prediabetic subjects with or without dyslipidaemia. The Cardiovascular Risk in Young Finns Study.

Laaksonen, Jaakko; Taipale, Tuukka; Seppälä, Ilkka; Raitoharju, Emma; Mononen, Nina; Lyytikäinen, Leo-Pekka; Waldenberger, Melanie; Illig, Thomas; Hutri-Kähönen, Nina; Rönnemaa, Tapani; Juonala, Markus; Viikari, Jorma; Kähönen, Mika; Raitakari, Olli; Lehtimäki, Terho.

Diabetes Metab Res Rev ; 33(7)2017 10.

Article in English | MEDLINE | ID: mdl-28609607

13.

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach.

Traylor, Matthew; Mäkelä, Kari-Matti; Kilarski, Laura L; Holliday, Elizabeth G; Devan, William J; Nalls, Mike A; Wiggins, Kerri L; Zhao, Wei; Cheng, Yu-Ching; Achterberg, Sefanja; Malik, Rainer; Sudlow, Cathie; Bevan, Steve; Raitoharju, Emma; Oksala, Niku; Thijs, Vincent; Lemmens, Robin; Lindgren, Arne; Slowik, Agnieszka; Maguire, Jane M; Walters, Matthew; Algra, Ale; Sharma, Pankaj; Attia, John R; Boncoraglio, Giorgio B; Rothwell, Peter M; de Bakker, Paul I W; Bis, Joshua C; Saleheen, Danish; Kittner, Steven J; Mitchell, Braxton D; Rosand, Jonathan; Meschia, James F; Levi, Christopher; Dichgans, Martin; Lehtimäki, Terho; Lewis, Cathryn M; Markus, Hugh S.

PLoS Genet ; 10(7): e1004469, 2014 Jul.

Article in English | MEDLINE | ID: mdl-25078452

14.

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.

Turpeinen, Hannu; Seppälä, Ilkka; Lyytikäinen, Leo-Pekka; Raitoharju, Emma; Hutri-Kähönen, Nina; Levula, Mari; Oksala, Niku; Waldenberger, Melanie; Klopp, Norman; Illig, Thomas; Mononen, Nina; Laaksonen, Reijo; Raitakari, Olli; Kähönen, Mika; Lehtimäki, Terho; Pesu, Marko.

Hum Genet ; 134(6): 627-36, 2015 Jun.

Article in English | MEDLINE | ID: mdl-25813623

15.

Non-coding 886 (nc886/vtRNA2-1), the epigenetic odd duck - implications for future studies.

Raitoharju, Emma; Rajic, Sonja; Marttila, Saara.

Epigenetics ; 19(1): 2332819, 2024 Dec.

Article in English | MEDLINE | ID: mdl-38525792

16.

Polygenic risk for schizophrenia, social dispositions, and pace of epigenetic aging: Results from the Young Finns Study.

Saarinen, Aino; Marttila, Saara; Mishra, Pashupati P; Lyytikäinen, Leo-Pekka; Raitoharju, Emma; Mononen, Nina; Sormunen, Elina; Kähönen, Mika; Raitakari, Olli; Hietala, Jarmo; Keltikangas-Järvinen, Liisa; Lehtimäki, Terho.

Aging Cell ; 23(3): e14052, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38031635

17.

Identification of gene networks jointly associated with depressive symptoms and cardiovascular health metrics using whole blood transcriptome in the Young Finns Study.

Mishra, Binisha H; Raitoharju, Emma; Mononen, Nina; Saarinen, Aino; Viikari, Jorma; Juonala, Markus; Hutri-Kähönen, Nina; Kähönen, Mika; Raitakari, Olli T; Lehtimäki, Terho; Mishra, Pashupati P.

Front Psychiatry ; 15: 1345159, 2024.

Article in English | MEDLINE | ID: mdl-38726387

18.

Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.

Markus, Hugh S; Mäkelä, Kari-Matti; Bevan, Steve; Raitoharju, Emma; Oksala, Niku; Bis, Joshua C; O'Donnell, Chris; Hainsworth, Atticus; Lehtimäki, Terho.

Stroke ; 44(5): 1220-5, 2013 May.

Article in English | MEDLINE | ID: mdl-23449258

19.

MicroRNAs in the atherosclerotic plaque.

Raitoharju, Emma; Oksala, Niku; Lehtimäki, Terho.

Clin Chem ; 59(12): 1708-21, 2013 Dec.

Article in English | MEDLINE | ID: mdl-23729638

20.

Coronary artery disease patient-derived iPSC-hepatocytes have distinct miRNA profile that may alter lipid metabolism.

Alexanova, Anna; Raitoharju, Emma; Valtonen, Joona; Aalto-Setälä, Katriina; Viiri, Leena E.

Sci Rep ; 13(1): 1706, 2023 01 30.

Article in English | MEDLINE | ID: mdl-36717592

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export: